fa پیش‌بینی وضعیت سیستم ایمنی از طریق شیوه‌های مقابله با استرس و تیپ شخصیتی D با میانجی‌گری مکانیسم‌های دفاعی در بیماران مبتلا به سرطان پستان تخصصي Special پژوهشي Research <br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">مقدمه:</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> سرطان پستان، به عنوان شایع&shy;ترین سرطان، علت مرگ و</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">میر میلیون&shy;ها نفر در سراسر جهان است. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">پژوهش حاضر با هدف ارائه مدل پیش بینی وضعیت سیستم ایمنی از طریق شیوه&shy;های مقابله با استرس و تیپ شخصیتی</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> با میانجی&shy;گری مکانیسم&shy;های دفاعی در بیماران مبتلا به سرطان پستان انجام شد. </span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">روش کار:</span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> جامعه آماری پژوهش حاضر شامل تمامی زنان مبتلا به سرطان پستان در شهر تهران و گیلان در سال 1398 بودند که از بین آنها</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> تعداد 250 با روش نمونه&shy;گیری هدفمند انتخاب شدند. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">داده&shy;ها با استفاده از فهرست وارسی علایم هشدار دهنده نقص سیستم ایمنی، پرسشنامه مکانیسم&shy;های دفاعی، پرسشنامه </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تیپ شخصیتی </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">D</span></span></span> <span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">و پرسشنامه راهبردهای مقابله با استرس جمع آوری شد.</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> داده&shy;ها شده با استفاده از </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">روش معادلات ساختاری </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تجزیه و تحلیل شدند و</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> نرم افزار</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">smart-PLS v3</span></span></span><span style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> آنالیز شد.</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""></span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">یافته&shy;ها:</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> یافته&shy;ها نشان داد، </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">شیوه&shy;های مقابله با استرس </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">اثر مستقیم معنی&shy;داری بر نمرات وضعیت سیستم ایمنی ندارد. اثر مستقیم </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تیپ شخصیتی</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">D</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">بر نمرات وضعیت سیستم ایمنی معنادار بود. </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">مکانیسم&shy;های دفاعی اثر میانجی&shy;گری در رابطه میان شیوه&shy;های مقابله با استرس و تیپ شخصیتی</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> با نمرات وضعیت سیستم ایمنی نداشت.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">نتیجه&shy;گیری:</span></span></span></b> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">به طور کلی چنین می&shy;توان نتیجه گرفت که</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:"> در بیماران مبتلا به سرطان پستان،</span></span></span> <span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تیپ شخصیتی</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">D</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">بر وضعیت سیستم ایمنی تاثیر معنی&shy;داری دارد </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">و</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">بنابراین </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">درمانگران و متخصصان سلامت می&shy;توانند با طراحی مداخلات مبتنی بر اصلاح </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">تیپ شخصیتی</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">، این افراد را در غلبه بر بیماری خود یاری رسانند</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span b="" mitra="" style="font-family:">.</span></span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span></span><br> &nbsp; <br> <span style="font-size:11pt"><span style="line-height:115%"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Introduction</span></span></span></b><b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""> Breast cancer, as the most common cancer, is the cause of death of millions of people around the world. The aim of this study was to present a model for predicting the status of the immune system through coping strategies with stress and personality type D mediated by defense mechanisms in patients with breast cancer. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Methods</span></span></span></b><b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""> The statistical population of the present study included all women with breast cancer in Tehran and Gilan in 2019, from which 250 were selected by purposive sampling. Data were collected using a checklist of warning signs of immunodeficiency, a questionnaire of defense mechanisms, a questionnaire of personality type D and a questionnaire of coping strategies. The data were analyzed using structural equation method and smart-PLS- v3 software was analyzed. </span></span></span><b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Results:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""> The results showed that coping strategies did not have a significant direct effect on immune status scores. The direct effect of personality type D on immune status scores was significant. Defense mechanisms did not mediate the relationship between coping styles with stress and personality type D with immune status scores. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:115%"><span sans-serif="" style="font-family:Calibri,"><b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b><b> </b><span style="font-size:12.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">In general, it can be concluded that in patients with breast cancer, personality type D has a significant effect on the state of the immune system, and therefore therapists and health professionals can design interventions based on the correction of personality type D, Help these people overcome their illness.</span></span></span></span></span></span><br> <br> &nbsp; سیستم ایمنی, استرس, تیپ شخصیتی D, مکانیسم­های دفاعی, سرطان پستان Immune system, Stress, Personality type D, Defense mechanisms, Breast cancer 101 116 http://ijpn.ir/browse.php?a_code=A-10-2010-1&slc_lang=fa&sid=1 Saghi kousha ساقی کوشا cp.kousha@gmail.com 27900319475328460015208 27900319475328460015208 No Health Psychology, department of Psychology, Rudehen Branch, Islamic Azad University, Rudehen, Iran. گروه روان شناسی، دانشگاه آزاد اسلامی واحد رودهن، رودهن، ایران Farah lotfi Kashani فرح لطفی کاشانی lotfi.kashani@gmail.com 27900319475328460015209 27900319475328460015209 Yes Department of psychology, Medical Sciences Branch, Islamic Azad University, Tehran, Iran گروه روانشناسی، واحد علوم پزشکی، دانشگاه آزاد اسلامی، تهران، ایران Shahram Vaziri شهرام وزیری 27900319475328460015210 27900319475328460015210 No Department of Psychology, Rudehen Branch, Islamic Azad University, Rudehen, Iran. گروه روانشناسی، واحد رودهن، دانشگاه آزاد اسلامی، رودهن، ایران Nahid Nafisi ناهید نفیسی 27900319475328460015211 27900319475328460015211 No Department of General Surgery, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), Iran University of Medical Sciences, Tehran, Iran گروه جراح عمومی مرکز تحقیقات بالینی تحقیقاتی جامع تحقیقاتی، دانشگاه علوم پزشکی ایران، تهران